Skip to main content

3 Substantial Dangers of Metformin Medicine

What are the three major Hazards of Metformin can be fatal if you ignore any of these?

Metformin is the first-line medication recommended in the guidelines for the prevention and treatment of type 2 diabetes. Not only can it improve insulin resistance and lower blood sugar, it can also prevent macrovascular and microvascular disease caused by diabetes, improve blood lipid metabolism, and reduce the chance of cardiovascular complications. Most people with diabetes need to take it for a long time. However, there are three issues that Metformin must pay attention to, otherwise it may cause harm or even threaten life at any time.


For providing or getting the Best Telehealth, Telegym services and fitness networking may Log in to fitcj .com  network

 

The 3 Issues are:

1. Long-term use of metformin will cause the loss of vitamin B12 and accelerate the occurrence of diabetic neuropathy

Vitamin B12 is an important substance that maintains the normal state of the body's hematopoietic function and can effectively prevent pernicious anemia. 

It can also exist in the form of coenzymes to regulate sugar metabolism. At the same time, it is also an essential vitamin for the nervous system.

 

For diabetics, the lack of vitamin B12 will not only affect the regulation of blood sugar, but also accelerate neuropathy and cause a variety of diabetic complications early. For example, diabetic peripheral neuropathy (lower limb numbness, pain, itching, etc.), diabetic cardiovascular disease (painless myocardial ischemia, painless myocardial infarction, etc.), diabetic foot (old rotten foot), etc.

Therefore, patients taking Metformin for a long time should add vitamin B12 appropriately. 

Vitamin B12 is abundant in meat, animal liver, fish, shellfish and eggs.

 

2. Very few patients taking metformin will induce lactic acidosis

Lactic acidosis is a very rare but very dangerous complication of diabetic patients. 

The clinical manifestations are vomiting, abdominal pain, and mental disorder. Once it occurs, the mortality rate is as high as 50%.

 

Lactic acid is a substance produced when glucose is metabolized under anaerobic conditions in cells. Under normal circumstances, most of the lactic acid can be converted into glucose again by the liver's xenobiosis, providing energy for the human body.


A small amount of lactic acid can be excreted by the kidney through metabolism. 

Metformin itself has the effect of inhibiting gluconeogenesis to glucose. It will cause the increase of lactic acid content in the body.

Metformin Dangers

If the patient has a serious loss of kidney function and lactic acid is difficult to metabolize through urination. It will accumulate too much in the human body and cause lactic acidosis. Therefore, patients with severe liver and kidney dysfunction are clinically prohibited from using metformin to prevent lactic acidosis.

 

3. Taking Metformin under three circumstances can easily cause hypoglycemia

Metformin itself does not cause hypoglycemia, but it can induce hypoglycemia in three situations, causing the patient's life to be dangerous.

 

1) After a lot of exercise, did not add enough calories in time;

 

2) Combination with sulfonylurea drugs or insulin may cause hypoglycemia;

 

3) After drinking alcohol, alcohol can stimulate insulin secretion, and it will reach a peak in 2-3 hours, which is the same as the peak period of the effect of hypoglycemic drugs. 

The two peaks are superimposed, which can easily cause hypoglycemia coma. This situation is often most easily overlooked by patients, and should be paid more attention to.

 

Although there may be the above risks, a large number of studies have shown that metformin is generally well tolerated, has high safety, and does not damage the liver and kidneys. 

It is still the drug of choice for diabetes control worldwide. 

Patients should be taken reasonably under the guidance of a doctor to obtain better treatment results.


Author's Bio



Name: Ian Skyler

Education: MBBS, MD

Occupation: Medical Doctor 

SpecializationCommunity Medicine, General Surgery, Natural Treatment

Experience: 18 Years as a Medical Practitioner

 

[[SHARE in Public Health Interest>>

Comments

Popular posts from this blog

How to Soften and Clean Blood Vessels?

The savior that softens the blood vessels is found, eat daily, remove garbage and blood vessels clean slowly The blood vessels are densely packed in the human body, and there are many branches, which are complicated. Blood supplies oxygen and oxygen to various organs and tissues through these blood vessels to ensure the health of the body. Once there is a problem with blood vessels, it will affect blood transport and cause abnormal phenomena, which is very detrimental to health. Among them, the occurrence of blood clots in blood vessels is very serious. It can cause hardening and blockage of blood vessels, which is extremely detrimental to the health of blood vessels. For providing or getting the Best Telehealth, Telegym services and fitness networking may log in to   fitcj .com   network   What is Blood Clot? It is often referred to as blood clot. In general, there are many reasons for the formation of thrombosis, mainly due to age. Sedentary inactivity, high stress in life,

What is Vaginitis Treatment and its Prevention?

Prevention and Treatment of Vaginitis Q. I am 22 years old and just had sex this month. This time after finishing my aunt's itching, there are a lot of secretions. Did I have vaginitis? Super scared, what should I do? What should I do if my female ticket got vaginitis? OR     I have fungal vaginitis. It has not been good to reuse the medicine for 2 months. It is really shameful. I dare not let my roommate find that there is no way to go to the hospital every day.     The vagina was very itchy after coming to the aunt this time. I am now physically and mentally broken. I was nineteen and still in college. I'm not that kind of casual girl. I dare not talk to my family about such things. Too scared.    Ans. Vaginitis Study For obstetrics and gynecology, vaginitis is really the disease we are most familiar with. More than 50% of obstetrics and gynecology clinics are due to vaginitis. There are also people who originally checked for other diseases. As a result, a l

Which Molecular POCT is stronger? Point-of-Care Testing

  Molecular POCT Point-of-Care Testing Strength If you want to know which product is most popular in medical devices exhibition, it is undoubtedly molecular detection , and the most popular molecular detection is undoubtedly molecular POCT (Point-of-Care Testing). Of course, most of the domestic molecular POCT manufacturers only have relevant concepts, and some of them cannot even exhibit physical machines. Therefore, the author has sorted out some western molecular POCT manufacturers' products for your reference and hope to encourage each other. For providing or getting Best Telehealth, Telegym services and fitness networking Log in to   fitcj .com   network   1. Cepheid Device model: GeneXpert GX-IV R2, GX-XVI R2, Infinity-48s, Infinity-80   Detection throughput: 4/16/48/80   Suitable products: hospital infection, virus detection, major infectious diseases, sexually transmitted infections, tumor-related disease detection   NMPA registration status: equipment cer