Molecular point-of-care Testing (POCT) A point-of-care test (POCT) is a laboratory test performed near the patient's point of care. POCT provides rapid test results and can improve patient care. However, if performed incorrectly or used incorrectly, POCT can produce misleading results and require additional monitoring, increasing costs and risk to patients. Although most POCTs were eliminated in the Federal Clinical Laboratory Improvement Amendments of 1988, several considerations challenge their implementation. This chapter will focus on the advantages and limitations of POCT and describe how to manage the quality of POCT to achieve optimal patient outcomes. What are the point-of-care devices for under-detection of drug abuse? Point-of-care testing (POCT) devices are available at the bedside or in the doctor's office to test for drugs using a urine sample or oral fluid. The advantage of this test is the quick availability of results. The POCT unit uses immunoassay and lat