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How many Types of Toxicology Testing is done?

 

Toxicological testing plays an important role in ensuring the safety of food, cosmetics and chemical products. Toxicology is the applied medicine that studies the harmful effects of chemicals, including pharmaceuticals, environmental pollutants, and industrial chemicals. It is a science that studies the toxicity, severity, frequency and mechanism of toxic effects of chemical substances on organisms, as well as qualitative and quantitative evaluation of toxic effects. It is a discipline that predicts its harm to the human body and the ecological environment, and provides a scientific basis for determining the safety limit and taking preventive measures. Through animal experiments and human observations, the toxicity of a chemical and its potential hazards are elucidated, in order to evaluate the safety of human use of these chemical substances, and to provide a theoretical basis for the formulation of preventive measures, especially health standards.

 

What services do toxicology testers provide?

According to the different requirements of customers, toxicology testing labs provide you with the following services:

  • Chemicals  and Cosmetics
  • Acute inhalation toxicity test
  • Acute dermal toxicity test
  • Acute oral toxicity test
  • Acute eye irritation/corrosion test
  • Skin irritation/corrosion test
  • Skin Allergy Test (Skin Sensitization Test)
  • Salmonella typhimurium reverse mutation test (Ames test)
  • Skin phototoxicity test
  • In Vitro Mammalian Cell Chromosomal Aberration Assay
  • In vivo chromosomal aberration assay in mammalian bone marrow cells
  • In vivo mammalian bone marrow polychromatic erythrocyte micronucleus assay
  • Mammalian spermatogonia/primary spermatocytes chromosomal aberration test sperm abnormality test
  • Subacute Inhalation (14/28 Days) Toxicity Test
  • Subacute dermal (21/28 days) toxicity test
  • Subacute oral (28 days) toxicity test

 

 

Diagram showing What is Toxicology Testing

 

Product Toxicity/Safety Testing

  • Acute oral and dermal toxicity test
  • Skin irritation/corrosion test
  • Acute eye irritation/corrosion test
  • Skin allergy test
  • Skin phototoxicity test
  • Salmonella typhimurium/reverse mutation assay
  • In Vitro Mammalian Cell Chromosomal Aberration Assay
  • In vitro mammalian cell gene mutation assay
  • Mammalian bone marrow cell chromosomal aberration assay
  • In vivo mammalian cell micronucleus assay
  • Testicular Germ Cell Chromosomal Aberration Test

 


 

Disinfectant & Food

  • Acute oral toxicity test
  • Acute inhalation toxicity test
  • Skin irritation test
  • Acute eye irritation test
  • Vaginal mucosal irritation test
  • Skin allergy test
  • Subacute toxicity test
  • L5178Y cell gene mutation test
  • V79 cell gene mutation test
  • In vitro cytotoxicity assay
  • In Vitro Mammalian Cell Chromosomal Aberration Assay
  • mouse bone marrow polychromatic erythrocyte micronucleus test
  • Mammalian bone marrow cell chromosomal aberration assay
  • Testicular Germ Cell Chromosomal Aberration Test
  • Mouse sperm abnormality test
  • Subchronic toxicity test Acute toxicity test
  • Salmonella typhimurium/mammalian microsomal enzyme assay
  • Mouse testis chromosomal aberration test
  • Bone marrow micronucleus test
  • Mammalian bone marrow cell chromosomal aberration assay
  • Mouse sperm abnormality test
  • In vitro mammalian cell (V79/HGPRT) gene mutation assay
  • TK gene mutation test
  • 30-day and 90-day feeding trials
  • Teratogenicity test

 

 


 

 

Health products and Effects of health products

  • Toxicology test
  • Acute toxicity test
  • Salmonella typhimurium/mammalian microsomal enzyme assay
  • Mouse testis chromosomal aberration test
  • Bone marrow micronucleus test
  • Mammalian bone marrow cell chromosomal aberration assay
  • Mouse sperm abnormality test
  • In vitro mammalian cell (V79/HGPRT) gene mutation assay
  • TK gene mutation test
  • 30-day and 90-day feeding trials Functional assessment tests:
  • Enhance immune function
  • Auxiliary blood lipid lowering function animal test
  • Animal test on auxiliary hypoglycemic function
  • Antioxidant function animal test
  • Functional animal test for relieving physical fatigue
  • Functional animal test for improving hypoxia tolerance
  • Animal test with auxiliary protective function against radiation hazards
  • Animal test with auxiliary protective function against chemical liver injury
  • Laxative function animal test

 


Pesticides and Disposable Hygiene products

  • Acute oral, dermal and inhalation toxicity tests
  • Skin Allergy (Sensitization) Test
  • Subacute oral, dermal and inhalation toxicity tests
  • Eye irritation test
  • Mutagenicity test
  • Teratogenicity test
  • Subchronic toxicity test
  • Skin irritation test
  • Vaginal mucosal irritation test
  • Skin allergy test

 

 

 Medical equipment and Fertilizers

  • In vitro cytotoxicity assay
  • In vitro cytotoxicity assay

 

 Water wading products and Toxicity/safety testing of other products

  • Acute Oral Toxicity Test
  • Test Protocol Consulting



Toxicology Overview

Toxicology is the science that studies the damage/harmful effects and mechanisms of exogenous chemicals, physical and biological factors on organisms and ecosystems, as well as the prevention, diagnosis and treatment of poisoning.

 

Toxicology, also known as toxicology, is the study of the harmful effects of exogenous chemicals and physical and biological factors on biological organisms and their mechanism of action, and then to predict the severity of their harm to the human body and the ecological environment.

The science that provides scientific basis for taking control measures is also a subject for qualitative and quantitative evaluation of toxic effects. 

Through animal experiments, clinical observations and on-site investigations, the toxicity, poisoning amount, intrusion route, poisoning mechanism, and pathological process of poisons are studied, and the basis for diagnosis, treatment, prevention of poisoning and the formulation of relevant health standards are provided.

According to different research objects, it is divided into clinical toxicology (drugs and toxicants encountered in daily life), industrial toxicology (productive toxicants), radiotoxicology (radioactive substances, food toxicology (harmful substances in food), Military toxicology (war agents), insect toxicology (interaction between insecticides and insects), etc.

There are also branches classified by system and organ, such as neurotoxicology, liver toxicology, and skin toxicology.

 

Since the purpose of toxicology research is to provide a scientific basis for the protection of the health or safety of organisms, toxicology belongs to preventive medicine in terms of the nature of the discipline, and runs through the idea of ​​prevention first.

 

Toxicology is closely related to pharmacology, and has now developed into an independent discipline with certain basic theories and experimental methods, and has gradually formed some new branches of toxicology. 

Toxicology can be divided into industrial toxicology, military toxicology, environmental toxicology, pharmaceutical toxicology, forensic toxicology and radiotoxicology according to its research purpose and the characteristics and uses of the chemical substances studied.

 

What are the Research Objects of Toxicology?

Toxicology has a wide range of research objects, including chemical factors, physical factors, and biological factors, and organisms include humans, animals, and plants. Therefore, toxicology is related to pharmacology, physiology, pathology, chemistry, biochemistry and biology.

It is related to industry, agriculture, economy, etc.

It is related to forensic science, clinical medicine, ecology and environmental protection

It can be said that it is related to the entire future of life on Earth is connected. Therefore, toxicology is widely used in clinical medicine, pharmacy, environmental protection, zoology, prenatal and postnatal care, occupational labor protection and food hygiene.

 

Classification of Toxicology

The classification of toxicology is very complex and can be classified from different angles, and it is not completely consistent.

From the research content, it can be divided into three parts: descriptive toxicology, mechanism toxicology and management toxicology (also known as regulatory toxicology).

It can be divided into: 

  • Forensic Toxicology
  • Clinical Toxicology
  • Management Toxicology or Regulatory Toxicology
  • Research Toxicology, etc.

 

From applied toxicology, it can be divided into: food toxicology, industrial toxicology, pesticide toxicology, military toxicology, radiotoxicology, environmental toxicology, ecotoxicology and other branches.

 

The research objects can be divided into: 

  1. Insect toxicology
  2. Veterinary toxicology
  3. Human toxicology 
  4. Plant toxicology

 

From the research fields, it can be divided into: drug toxicology, environmental toxicology, food toxicology, industrial toxicology, clinical toxicology, forensic toxicology, analytical toxicology, military toxicology, management toxicology, etc.

 

From the target organs or systems studied, it can be divided into: liver toxicology, renal toxicology, neurotoxicology, reproductive toxicology, immunotoxicology, skin toxicology, blood toxicology, etc.

 

From the mechanism research can be divided into:

  • Cytotoxicology
  • Genetic toxicology
  • Membrane toxicology
  • Biochemical toxicology
  • Molecular toxicology

From the phase or process of toxic action, it can be divided into: toxicokinetics and toxicodynamics.

 

 What is toxicology journal?

Toxicology is a scientific academic journal published since 1973. Published 36 times a year, the journal investigates the positive effects of xenobiotics on human and other animal health. Currently, the editors-in-chief of the journal are H.W.J. Marquardt and K.B. Wallace of the Department of Toxicology, University of Hamburg, Germany. According to the 2012 Journal Citation Report, "Toxicology" has an impact factor of 4.017, ranking 17th out of 50 toxicology journals.


Author's Bio



Name: Ian Skyler

Education: MBBS, MD

Occupation: Medical Doctor 

SpecializationCommunity Medicine, General Surgery, Natural Treatment

Experience: 18 Years as a Medical Practitioner

 


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