Research reveals the mystery of brain-eating amoeba targeting the brain Nagri Amoeba flexneri is small and sinister. All it needs is liquid splash. Brain-eating amoeba (amoeba) will enter the swimmer's brain through the nose unconsciously. Once something happens, the chance of survival of the intruder is almost zero. "They have food cups that look like giant suckers on their bodies," says Francine Cabral of Virginia Commonwealth University in Richmond, USA. "Then they will start eating their brains."   Now, researchers have discovered why there is a close relationship between this deadly amoeba and the brain. This research breakthrough is expected to develop life-saving drugs.   This amoeba, called Nagri Amoeba flexneri, usually lurks in fresh water, but it sometimes causes infections in hot springs and unhealthy chlorinated swimming pools. In the 35 cases reported in the United States from 2005 to 2014, there were only two survivors. In August of th

  First in the world: The Lancet China COVID-19 vaccine human trial data This is the world's first official COVID-19 vaccine human clinical trial results, and it is also the world's first show of adenovirus carrier COVID-19 vaccine. The results are quite optimistic.   Previous discussions on the effectiveness of the COVID-19 vaccine focused on antibodies (humoral immunity), which may have caused the public to misunderstand that the effectiveness of the vaccine is only reflected in antibodies.  This study mentioned the importance of cellular immunity, and then discussing the performance of vaccines, we should consider both antibodies and cellular immunity. Aadenovirus vector vaccine from Academician Chen Wei is safe, says The Lancet In the middle of the night on May 22, the international authoritative medical journal "The Lancet" published online the results of the world's first human clinical trial of a COVID-19 vaccine, showing that the adenovirus vec

Is the new coronavirus artificial? Was it leaked from the laboratory? Latest evidence is here The epidemic of the new crown virus is spreading globally, and there is no conclusion as to the origin of the virus. Today, six top scientists from the United States, the United Kingdom, and Australia published articles in the authoritative Nature Medicine journal, pointing out the possible source of the virus.     The new crown virus has 3 different characteristics Through genetic analysis of the new coronavirus and comparing it with other known coronaviruses, scientists have discovered that the new coronavirus has three significant characteristics.   1. The combination with ACE2 is unique Like the SARS coronavirus, the new coronavirus also binds to human ACE2, and then enters human cells to cause infection.  It can be simply understood that there is a key on the virus, which can open the lock on our human cells. After the virus opens the door, it enters the human cell.   Ho

  What do you think of the low antibody value of China's COVID-19 vaccine? A hidden worry about vaccines in China Putting aside the value part of this table that attracts attention, what is really important is the choice of vaccine antigen. At this point, there is a hidden worry about vaccines in China, which is worthy of detailed analysis and pointing out. On August 13, the results of phase I/II human clinical trials of the inactivated COVID-19 vaccine of Zhongsheng Group Wuhan Biotechnology were published in the international medical journal Journal of the American Medical Association , becoming the world's first officially published clinical trial data of an inactivated vaccine , The data on immunogenicity has attracted the attention of the industry.   Weibo netizen is a netizen who is engaged in biomedical research in the United States. He compiled the seven vaccines that have released immunogenicity data into a table for reference and comparison.   In the table

Preliminary Study on the Mechanism of Coronavirus ADE Effect Coronavirus has an ADE effect is a fact that many people know. Many studies in vivo and in vitro have confirmed this. This is also a major obstacle to the development of a vaccine against the new coronavirus. Understanding the ADE mechanism of the coronavirus will be the key to designing a vaccine that can avoid the production of ADE.   This article is very dry, onlookers can pull it down to read the conclusion and just like it.   This article will expand from the following three aspects:   Introduction to the ADE effect Introduction to the phenomenon of coronavirus species ADE The mechanism of coronavirus ADE What is the ADE effect? ADE is the abbreviation of antibody-dependent enhancement , Chinese "antibody-dependent enhancement".   ADE or "antibody-dependent enhancement" was first discovered during dengue virus infection.   The main disease caused by dengue virus infection